ReSolvin EQ™ Special Needs Nutrition for Horses Predisposed to Gastric Ulcers

Equine gastric ulcer disease (EGUS) affects all classes of horses but is especially widespread among performance horses. Because of this, preventing and treating gastric ulcers remains a priority for those invested in the well-being of all horses. ReSolvin EQ™ is a revolutionary oil designed to support gastric health one meal at a time through strategic supplementation of long-chain polyunsaturated fatty acids.

Use ReSolvin EQ to increase the amount of long-chain polyunsaturated fatty acids in the diet and to protect horses from the adverse effects of gastric ulcers.

ReSolvin EQ: Targeted Supplementation for Gastric Health Support

Dietary supplementation of polyunsaturated fatty acids (PUFAs), particularly eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and gamma-linolenic acid (GLA), has been a key focus of research efforts due to their positive effects in the body. Virtually every body cell features membranes composed of PUFAs, and these membranes are extremely responsive to dietary supplementation.

A study performed by Kentucky Equine Research assessed the relationship between red blood cell PUFAs and the incidence of and severity of squamous gastric ulcers when horses were fed short-chain polyunsaturated fatty acids (SC-PUFAs) or long-chain polyunsaturated fatty acids (LC-PUFAs).*

Horses were evaluated by gastroscopy for squamous ulcer score, gastric pH, and blood fatty acid composition prior to supplementation and after three months of supplementation with a corn-flax oil blend, which included the SC-PUFAs alpha-linolenic acid (ALA) and linoleic acid (LA), or ReSolvin EQ, a source of LC-PUFAs that contained GLA, EPA, and DHA.

Three months of supplementation with ReSolvin EQ increased red blood cell levels of GLA, EPA, DHA, DGLA (di-homo-gamma-linolenic acid) and AA (arachidonic acid) and reduced severe ulcer prevalence (38% in unsupplemented horses vs. 8% in horses supplemented with LC-PUFAs with a severe ulcer score, grade 3-4). SC-PUFA supplementation did not significantly elevate red blood cell GLA, EPA, DHA, DGLA, or AA, and severe ulcer incidence was not different (38% in unsupplemented horses vs. 23% in horses supplemented with SC-PUFAs with a severe ulcer score). Lower levels of red blood cell GLA, DGLA, AA, and EPA correlated with severe squamous gastric ulceration.

Figure 1. The incidence of squamous ulcer scores of 0, 1 to 2, and 3 to 4 per treatment in the aforementioned study.

In summary, targeted supplementation with ReSolvin EQ, a blend of EPA, DHA, and GLA, provides a potent anti-inflammatory product for horses predisposed to gastric ulcers. Read the ReSolvin EQ Technical Bulletin for an in-depth look at EGUS and the benefits of LC-PUFA supplementation.


Long-chain PUFA supplementation increased levels of GLA, EPA, DHA, DGLA, and AA, unlike short-chain PUFA supplementation, and was associated positively with prevention or resolution of severe squamous gastric ulceration.
Read the Research


Feeding Instructions

For use in equines only. Top-dress 60 mL per day on feed, divided equally between two meals. Horses fed ReSolvin EQ should also be fed a vitamin E supplement with superior bioavailability.

*grams per 100 grams of fatty acid

ReSolvin EQ Technical Review Sheet


Pagan, J.D., A.A. Hauss, E.C. Pagan, J.L. Simmons, and B.M. Waldridge. 2022. Long-chain fatty acid supplementation increases levels in red blood cells and reduces the prevalence and severity of squamous gastric ulcers in exercised Thoroughbreds. Journal of the American Veterinary Medical Association. doi:10.2460/javma22.06.0275.

About KERx Special Needs Nutrition

KERx is a division of KER Targeted Nutrition featuring products developed by Kentucky Equine Research and recommended by veterinarians to support specific nutrition-related challenges.

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